UCT Silane Cited in Cellular Research Article

Wednesday, September 27th, 2017

In a recent article published in Lab on Chip by E.L. Jackson-Holmes et al., (DOI: 10.1039/C7LC00763A), tridecafluoro-1,1,2,2-tetrahydrooctyl-1-trichlorosilane from UCT was integral in the production of a mold to perform their intended research. In the procedure, a master mold was fabricated by standard UV photolithography with the negative photoresist to create three layers of respective heights 200 μm, 100 μm, and 200 μm. In making the polydimethylsilane (PDMS) molding, the master was treated with the UCT silane vapor to allow release of the PDMS. These three-dimensional pluripotent stem cell (PSC) cultures have the ability to undergo differentiation, self-organization, and morphogenesis to yield complex, in vitro tissue models that recapitulate key elements of native tissues.  For more information on UCT specialty chemicals visit

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