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UCT’s DETA cited in Stem Cell Research Study

In a recent paper authored by Navaneetha Santhanam et al, published in Biomaterials ((2018) 166 64-78), UCT’s specialty chemical 3-trimethoxysilyl propyl diethylenetriamine (DETA), an amine-terminated alkylsilane, was employed to promote cell adhesion. This study was designed to develop and evaluate a prototype of a drug-screening platform for neuromuscular junctions at different modes of operation: presynaptic and/or postsynaptic

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DAU Sorbent cited in Equine Toxicology Study

In a recent study published in Drug Testing and Analysis (DOI: 10.1002/dta.2378), authored by Heather K. Knych et al, UCT’s Clean Screen® DAU was employed to extract grapiprant following oral administration to exercised thoroughbred horses. Grapiprant is a newly approved non‐ cyclooxygenase inhibiting non‐steroidal anti‐inflammatory drug that has demonstrated efficacy and safety in other species. As long‐term use of these drugs can adversely impact the health of the horse, anti‐inflammatories with a more favorable safety profile are warranted.

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UCT Specialty Chemical cited in Mechanobiology Study

In a recent article published in Lab on a Chip, authors Donghee Lee et al., (DOI: 10.1039/C8LC00320C), used UCT’s specialty chemical (Tridecafluoro-1, 1, 2, 2-Tetrahydrooctyl)-1- Trichlorosilane (T2492-KG) in a mold-making process. This involved the production of a microfluidic cell compression device that improved a microfluidic device proposed previously by equipping it with an array of cell compression units. The device contained a 5×5 array of alginate-chondrocyte constructs. This microfluidic cell was employed to investigate human cartilage cells. T2492-KG played an integral part of this procedure.

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