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Blog

UCT Silane Cited in Plasmon Research Study

Monday, October 01st, 2018

Ultrasensitive and selective detection and quantification of dopamine (DA) plays a key role in monitoring neurodegenerative diseases and the detection limit reported is typically in the lower nanomolar range. Pushing the detection limit to picomolar (pM) or lower for this particular target to cover the physiological levels (< 130 pM) is significant. In the following article, DA DNA aptamer (DAAPT) gold nanoparticle (AuNP) conjugate is utilized to enhance the surface plasmon resonance (SPR) signal, which enables to detect and quantify DA in the femtomolar (200 fM) to pM range.